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Yi-Wen Chen Assistant Professor

Tel:886-2-23123456 ext 67412


D.D.S. in Dentistry, Taipei Medical University, 2000
Ph.D. in Periodontology, Tokyo Medical and Dental University, 2007

Professional specialties

1. Periodontics
2. Oral Microbiology

Main Research Interests

1. Diagnosis and Pathology of Periodontal diseases
2. The associations between Periodontitis and Vascular diseases

Oral microbiology
1. Inflammations induced by periodontal pathogens
2. Specific immune responses stimulated by periodontal pathogens

Selected Publications

  1. Lee BS, Lee CC, Wang YP, Chen HJ, Lai CH, Hsieh WL, Chen YW (2016). Controlled-release of tetracycline and lovastatin by PLGA-chitosan nanoparticles enhances periodontal regeneration in dogs. Journal of International Journal of Nanomedicine 11:285-97.(SCI)
  2. Wang CY, Chyuan IT, Wang YL, Kuo MY, Chang CW, Wu KJ, Hsu PN, Nagasawa T, Wara-Aswapati N, Chen YW (2015). β2-glycoprotein I-dependent anti-CL antibodies associated with periodonitis in SLE patients. Journal of Periodontology 86:995-1104. (SCI)
  3. Chang MC, Tsai YL, Chen YW, Chan CP, Huang CF, Lan WC, Lin CC, Lan WH, Jeng JH (2013). Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts. Journal of Periodontal Research 48(1):66-73. (SCI)
  4. Chen YW YW, Wang MY, Chang HH, Yen-Ping Kuo M. (2012). Curcumin Inhibits Thrombin-Stimulated Connective Tissue Growth Factor (CTGF/CCN2) Production Through JNK Suppression in Human Gingival Fibroblasts. Journal of Periodontology, 83(12):1546-53. (SCI)
  5. Chen YW, Nagasawa T, Wara-Aswapati N, Ushida Y, Wang DQ, Takeuchi Y, Kobayashi H, Umeda M, Inoue Y, Iwai T, Ishikawa I, Izumi Y (2009). Association between periodontitis and anti-cardiolipin antibodies in Buerger disease. Journal of Clinical Periodontology 36(10):830-35.
  6. Chen YW, Umeda M, Nagasawa T, Takeuchi Y, Huang Y, Inoue Y, Iwai T, Izumi Y, Ishikawa I (2008). Periodontitis may increase the risk of peripheral arterial disease. European Journal of Vascular and Endovascular Surgery 35(2):153-58.
  7. Li XF, Iwai T, Nakamura H, Inoue Y, Chen YW, Umeda M, Suzuki H (2008). An ultrastructural study of Porphyromonas gingivalis-induced platelet aggregation. Thrombosis Research 122(6):810-19.
  8. Wang D, Nagasawa T, Chen Y, Ushida Y, Kobayashi H, Takeuchi Y, Umeda M, Izumi Y (2008). Molecular mimicry of Aggregatibacter actinomycetemcomitans with beta 2 glycoprotein I. Oral Microbiology and Immunology 23(5):401-05.
  9. Chen YW, Iwai T, Umeda M, Nagasawa T, Huang Y, Takeuchi Y, Ishikawa I (2007). Elevated IgG titers to periodontal pathogens related to Buerger disease. International Journal of Cardiology 122:79-81.
  10. Chen ZY, Takahashi M, Naruse T, Nakajima T, Chen YW, Inoue Y, Ishikawa I, Iwai T, Kimura A (2007). Synergistic contribution of CD14 and HLA loci in the susceptibility to Buerger disease. Human Genetics 122:367-72.