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Mark Yen-Ping Kuo Professor

Tel:886-2-23123456 ext 67412
Email:oddie@ntu.edu.tw


Experiences

D.D.S., Dentistry, National Taiwan University, 1982
Ph. D., Molecular Biology, University of Pennsylvania, USA, 1989

Professional specialties

Periodontics
Oral Molecular Biology

Main Research Interests

  1. Molecular pathogenesis of areca-quid chewing related oral diseases: oral cancer, oral submucous fibrosis
  2. Development of novel strategies for the treatment of oral cancer and oral oral submucous fibrosis, including target therapy, gene therapy and new chemotherapeutic agents
  3. Roles of periodontal pathogens in the development of atherosclerosis
  4. Cancer and periodontal stem cells

Selected Publications

     
  1. Chang JZC, Hsieh YP, Lin WH, Chen HM and Kuo MYP (2017). Activation of transforming growth factor-1 by thrombin via integrins v1, v3, and v5 in buccal fibroblasts: Suppression by epigallocatechin-3-gallate. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 39: 1436-1445. (SCI)
  2. Wu PH, Chung HY, Wang JH, Shih JC, Kuo MYP, Chang PC, Huang YD, Wang PC and Chang CC (2016). Amniotic membrane and adipose-derived stem cell co-culture system enhances bone regeneration in a rat periodontal defect model. Journal of the Formosan Medical Association 115: 186-194.(SCI)
  3. Hsieh YP, Chen HM, Chang JZC, Chiang CP, Deng YT and Kuo MYP (2015). Arecoline stimulated early growth response-1 production in human buccal fibroblasts: Suppression by epigallocatechin-3-gallate. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 37: 493-497. (SCI)
  4. Chang PC, Chong LY, Dovban ASM, Lim LP, Lim JC, Kuo MYP and Wang CH (2014). Sequential Platelet-Derived Growth Factor-Simvastatin Release Promotes Dentoalveolar Regeneration. Tissue Engineering Part A 20: 356-364. (SCI)
  5. Hou HH, Cheng SL, Chung KP, Kuo MYP, Yeh CC, Chang BE, Lu HH, Wang HC and Yu CJ (2014). Elastase induces lung epithelial cell autophagy through placental growth factor A new insight of emphysema pathogenesis. Autophagy 10: 1509-1521. (SCI)
  6. Yang WH, Deng YT, Kuo MYP, Liu CM, Chang HH and Chang JZC (2013). Epigallocatechin-3-gallate Blocks Triethylene Glycol Dimethacrylate-induced Cyclooxygenase-2 Expression by Suppressing Extracellular Signal-regulated Kinase in Human Dental Pulp and Embryonic Palatal Mesenchymal Cells. Journal of Endodontics 39: 1407-1412. (SCI)
  7. Chang PC, Chien LY, Yeo JF, Wang YP, Chung MC, Chong LY, Kuo MYP, Chen CH, Chiang HC, Ng BN, Lee QQ, Phay YK, Ng JR and Erk KY (2013). Progression of Periodontal Destruction and the Roles of Advanced Glycation End Products in Experimental Diabetes. Journal of Periodontology 84: 379-388. (SCI)
  8. Cheng SJ, Kok SH, Lee JJ, Kuo MYP, Cheng SL, Huang YL, Chen HM, Chang HH, Chiang CP (2012). Significant association of SRC protein expression with the progression, recurrence, and prognosis of oral squamous cell carcinoma in Taiwan. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 34(9):1340-45. (SCI)
  9. Chang JZC, Yang WH, Deng YT, Chen HM, Kuo MYP (2012). Thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production in human buccal mucosal fibroblasts: Inhibition by epigallocatechin-3-gallate. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 34(8):1089-94. (SCI)
  10. Cheng SJ, Lee JJ, Cheng SL, Chen HM, Chang HH, Wang YP, Kok SH, Kuo MYP, Chiang CP (2012). Increased serum placenta growth factor level is significantly associated with progression, recurrence and poor prognosis of oral squamous cell carcinoma. Oral Oncology 48(5):424-28. (SCI)
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