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Jiiang-Huei Jeng Professor

Tel:886-2-23123456 ext 67400


DDS, Dentistry, National Taiwan University, 1985
PhD, Dentistry, National Taiwan University, 1994

Diplomate of Academy of Endodontology, ROC
Diplomate of Academy of Periodontology, ROC

Professional specialties

  1. Endodontics
  2. Periodontics
  3. Areca Medicine
  4. Oral Pharmacology & Toxicology
  5. Material Biocompatibility

Main Research Interests

Betel quld chewing and oral mucosal diseases

To clarify the effects of areca nut, piper betle inflorescence, and lime on the metabolism and behavior of human oral mucosal cells will facilitate our understanding the mechanisms of betel quid carcinogenesis and possible chemoprevention in the future.

Growth factors on the behavior of human dental pulp and periodontium

Growth factors are important during the development of human dental pulp and periodontium. In addition, they can regulate the repair and regeneration of human dental pulp and periodontal tissues following injury. Clarifying the effects of growth factors on the metabolism and behavior of pulp and periodontal cells will be increasingly important for clinical vital pulp therapy and periodontal regeneration.

Toxicology and pharmacology of various dental materials

Various dental medicaments, materials and their components were tested for the cytotoxicity, genotoxicity, mutagenicity, inflammatory mediator release, and its effect on systemic health. The related toxic mechanisms such as cell cycle, redox changes, apoptosis, and the gene alterations by the toxic ingredients were also evaluated.

Selected Publications

  1. Liao WC, Tsai YL, Wang CY, Chang MC, Huang WL, Lin HJ, Liu HC, Chan CP, Chang SH and Jeng JH (2017). Clinical and Radiographic Characteristics of Vertical Root Fractures in Endodontically and Nonendodontically Treated Teeth. Journal of Endodontics 43: 687-693. (SCI)
  2. Chang YC, Chang MC, Chen YJ, Liou JU, Chang HH, Huang WL, Liao WC, Chan CP, Jeng PY and Jeng JH (2017). Basic Fibroblast Growth Factor Regulates Gene and Protein Expression Related to Proliferation, Differentiation, and Matrix Production of Human Dental Pulp Cells. Journal of Endodontics 43: 936-942. (SCI)
  3. Chang MC, Lin SI, Lin LD, Chan CP, Lee MS, Wang TM, Jeng PY, Yeung SY, Jeng JH (2016). PGE2 stimulates EP2, adenylate cyclase, phospholipase C and intracellular calcium release to mediate cAMP production in dental pulp cells. Journal of Endodontics 42(3):584-588.(SCI)
  4. Chang MC, Tsai YL, Chang HH, Lee SY, Lee MS, Chang CW, Chan CP, Cheng RH, Jeng JH (2016). IL-1beta-induced MCP-1 expression and secretion of human dental pulp cells is related to TAK1, MEK/ERK and PI3K/Akt signaling pathways. Archives of Oral Biology 61:16-22. (SCI)
  5. Chang MC, Hung HP, Lin LD, Shyu YC, Wang TM, Lin HJ, Chan CP, Huang CC and Jeng JH (2015). Effect of interleukin-1 beta on ICAM-1 expression of dental pulp cells: role of PI3K/Akt, MEK/ERK, and cyclooxygenase. Clinical Oral Investigations 19: 117-126. (SCI)
  6. Huang CC, Chang YC, Chuang MC, Lin HJ, Tsai YL, Chang SH, Chen JC and Jeng JH (2014). Analysis of the Width of Vertical Root Fracture in Endodontically Treated Teeth by 2 Micro-Computed Tomography Systems. Journal of Endodontics 40: 698-702. (SCI)
  7. Chang HH, Chang MC, Wang HH, Huang GF, Lee YL, Wang YL, Chan CP, Yeung SY, Tseng SK and Jeng JH (2014). Urethane dimethacrylate induces cytotoxicity and regulates cyclooxygenase-2, hemeoxygenase and carboxylesterase expression in human dental pulp cells. Acta Biomaterialia 10: 722-731. (SCI)
  8. Chang MC, Tsai YL, Chen YW, Chan CP, Huang CF, Lan WC, Lin CC, Lan WH, Jeng JH (2013). Butyrate induces reactive oxygen species production and affects cell cycle progression in human gingival fibroblasts. Journal of Periodontal Research 48(1):66-73. (SCI)
  9. Lee JJ, Cheng SJ, Wang YP, Jeng JH, Chiang CP, Kok SH (2013). Osteonecrosis of the jaws associated with the use of yearly zoledronic acid: Report of 2 cases. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 35(1):E6-E10. (SCI)
  10. Chang HH, Chang MC, Huang GF, Wang YL, Chan CP, Wang TM, Lin PS, Jeng JH (2012). Effect of triethylene glycol dimethacrylate on the cytotoxicity, cyclooxygenase-2 expression and prostanoids production in human dental pulp cells. International Endodontic Journal 45(9):848-58. (SCI)
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