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郭彥彬 教授

電話:23123456 ext 67412
Email:oddie@ntu.edu.tw


學經歷

國立台灣大學牙醫學士,民國七十一年
美國賓夕法尼亞大學博士,民國七十八年

專長

  1. 一般牙科
  2. 牙周病

主要研究領域

  1. 台灣地區口腔癌之分子致癌機轉
  2. 發展以survivin基因為標的之口腔癌基因療法
  3. Histone deacetylase(HDAC)在口腔癌致癌機轉中扮演的角色及以HDAC抑制劑做為口腔癌治療藥物潛力之研究
  4. 探討新興藥物作為口腔癌化學治療與化學預防之效果
  5. 利用噬菌體顯現法技術篩選腫瘤專一性胜肽作為台灣口腔癌治療之研究
  6. 口腔黏膜下纖維化症的分子病理學研究
  7. 牙周致病菌在動脈硬化中扮演角色之研究
  8. 口腔癌及牙周組織幹細胞之研究

研究著作選列

     
  1. Wu PH, Chung HY, Wang JH, Shih JC, Kuo MYP, Chang PC, Huang YD, Wang PC and Chang CC (2016). Amniotic membrane and adipose-derived stem cell co-culture system enhances bone regeneration in a rat periodontal defect model. Journal of the Formosan Medical Association 115: 186-194.(SCI)
  2. Hsieh YP, Chen HM, Chang JZC, Chiang CP, Deng YT and Kuo MYP (2015). Arecoline stimulated early growth response-1 production in human buccal fibroblasts: Suppression by epigallocatechin-3-gallate. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 37: 493-497. (SCI)
  3. Chang PC, Chong LY, Dovban ASM, Lim LP, Lim JC, Kuo MYP and Wang CH (2014). Sequential Platelet-Derived Growth Factor-Simvastatin Release Promotes Dentoalveolar Regeneration. Tissue Engineering Part A 20: 356-364. (SCI)
  4. Hou HH, Cheng SL, Chung KP, Kuo MYP, Yeh CC, Chang BE, Lu HH, Wang HC and Yu CJ (2014). Elastase induces lung epithelial cell autophagy through placental growth factor A new insight of emphysema pathogenesis. Autophagy 10: 1509-1521. (SCI)
  5. Yang WH, Deng YT, Kuo MYP, Liu CM, Chang HH and Chang JZC (2013). Epigallocatechin-3-gallate Blocks Triethylene Glycol Dimethacrylate-induced Cyclooxygenase-2 Expression by Suppressing Extracellular Signal-regulated Kinase in Human Dental Pulp and Embryonic Palatal Mesenchymal Cells. Journal of Endodontics 39: 1407-1412. (SCI)
  6. Chang PC, Chien LY, Yeo JF, Wang YP, Chung MC, Chong LY, Kuo MYP, Chen CH, Chiang HC, Ng BN, Lee QQ, Phay YK, Ng JR and Erk KY (2013). Progression of Periodontal Destruction and the Roles of Advanced Glycation End Products in Experimental Diabetes. Journal of Periodontology 84: 379-388. (SCI)
  7. Cheng SJ, Kok SH, Lee JJ, Kuo MYP, Cheng SL, Huang YL, Chen HM, Chang HH, Chiang CP (2012). Significant association of SRC protein expression with the progression, recurrence, and prognosis of oral squamous cell carcinoma in Taiwan. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 34(9):1340-45. (SCI)
  8. Chang JZC, Yang WH, Deng YT, Chen HM, Kuo MYP (2012). Thrombin-stimulated connective tissue growth factor (CTGF/CCN2) production in human buccal mucosal fibroblasts: Inhibition by epigallocatechin-3-gallate. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 34(8):1089-94. (SCI)
  9. Cheng SJ, Lee JJ, Cheng SL, Chen HM, Chang HH, Wang YP, Kok SH, Kuo MYP, Chiang CP (2012). Increased serum placenta growth factor level is significantly associated with progression, recurrence and poor prognosis of oral squamous cell carcinoma. Oral Oncology 48(5):424-28. (SCI)
  10. Yeh CC, Hsieh HL, Lee J, Jan YH, Lai TC, Hong CY, Hsiao M, Kuo MYP (2011). Polyethylenimine-mediated PUMA gene delivery to orthotopic oral cancer: Suppression of tumor growth through apoptosis induction in situ and prolonged survival. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 33(6):878-85. (SCI)