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侯連團 兼任教授

電話:23123456 ext 66854
Email:lthou@ntu.edu.tw


學經歷

學歷:
國立臺灣大學牙醫學士,民國六十二年
國立臺灣大學牙周病學專科,民國六十八年
美國康乃狄克大學口腔生物學博士,民國七十六年

經歷:
中華民國牙周病醫學會理事長
台大醫院牙周病科主任

專長

  1. 牙周再生手術
  2. 牙周美容手術
  3. 骨脊增寬術

主要研究領域

  1. 藥物誘發牙齦腫大之細胞生物學研究:
    器官移植所導致藥物性牙齦腫大在台灣有增多之趨勢。本實驗室目前正收集臨床上牙齦腫大病例,取切片(活體)培養細胞,並分析其生長曲線DNA合成勺蛋白質代謝及金屬蛋白晦及其抑制劑,以了解其致病機制。藥物誘發牙齦腫大細胞模型之建立亦正進行中。
  2. Interleukm-1β在牙周病之病源發生的角色:
    interleukm-1β乃在牙周病產生過程中涉及軟組織之分解和骨組織之吸收的炎性先期調理素,此種因子可刺激牙周組織內之各種炎性細胞和原地組織細胞釋放出分解組織基質之酵素。因此牙周病發生時分泌Interleukin-1β乃之細胞之標定。分佈及與臨床嚴重度之柑關性則為研究重點。

研究著作選列

  1. L.-T HOLI (1993) Study of Collagen and Fibronection in Fibroblasts Derived from Healthy and Diseased Periodontal Tissues. J Formosan Med. Asso. 92: 367-372
  2. L.-T Hou, C.-M Liu and Wen-Kuei Chang (1994) Alkaline Phosphatase Activity in Cultured Cells of Healthy and Hyperplastic Gingivae. J Formosan Med Asso. 93 (10):870-74.
  3. L.-T Hou and J.A Yaeger (1995) Alkaline Phosphatase Expression in Cells Isolated from Different Overgrown Gingival Tissues. J Oral Path Med 24:97-102.
  4. L.-T Hou, C.-M Liu, and W.-K Chang (1994) Increased interleukin-lp in Gingival Crevicular Fluid of Chinese Periodontal patients. J Formosan Med Asso. 93:99-103.
  5. L.-T Hou, C.-M Liu and E.F Rossomando (1995): Crevicular interleukin-IB in moderate and severe periodontitis patients and the effect of phase I periodontal treatment. J Clin Periodontol 22 (2): 162-167.
  6. C-M Liu, L-T Hou, M-Y Wong and E F, Rossomando (1996) Relationship among clinical parameters, interleukin-lp and histopathologic findings of gingival tissue in periodontitis patients. Cytokine 8: 168-177, 1996.
  7.  L-H Hou, C-M LIU, S-C PEI, and E.F. Rossomando: Interleukin-lp Activity and Matched Histopathologic Findings of Biopsy Gingival Tissue From periodontitis Patients. J Periodontol (potentially accepted).