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江俊斌 名譽教授

電話:23123456 ext 67407
Email:cpchiang@ntu.edu.tw


學經歷

國立台灣大學牙醫學士,民國六十六年
美國哈佛大學醫學科學博士,民國七十八年

專長

  1. 口腔病理學
  2. 口腔組織學
  3. 免疫組織化學
  4. 光動力治療

主要研究領域

  1. 口腔病變之免疫組織化學研究:
    本研究主要利用單株或多株抗體及免疫組織化學染色法,探討致癌基因、抑癌基因、生長因子、生長因子受器、細胞角質於口腔癌前病變、口腔癌、唾液腺腫瘤,齒源性囊腫和齒源性腫瘤之表現,進一步探討這些特殊蛋白質表現和口腔習性,臨床參數(患者性別、年齡、腫瘤部位、腫瘤大小、淋巴結轉移、臨床分期)及組織病理學參數之相關性。此研究對口腔癌前病變之惡性潛能和口腔病變之致病機轉的了解,將有很大的助益。
  2. 口腔癌前和癌病變之光動力診斷與治療:
    近年來我們發展自體螢光光譜和染料螢光光譜 (5-ALA導引之protoporphyrine IX (PpIX) 螢光光譜) 來協助口腔癌前和癌病變之診斷。我們的研究發現,以330 nm的激發光量測之自體螢光光譜,及以410 nm的激發光量測之ALA 導引之PpIX螢光光譜,可幫助分辨口腔黏膜下纖維化症 (OSF),正常口腔黏膜,口腔癌前病變和口腔癌。因此利用此自體螢光光譜和染料螢光光譜技術,將可於大範圍口腔白斑或紅斑性病變中決定適當的切片位置。另外局部塗抹20% ALA之光動力治療,也可以作為口腔癌前病變和口腔癌之輔助療法,我們的研究發現其對疣狀增生和紅白斑的治療效果很好,也很有潛力可用以治療疣狀癌及早期口腔癌。

 

研究著作選列

     
  1. Sun A, Chang JYF, Wang YP, Cheng SJ, Chen HM, Chiang CP (2016). Do all the patients with vitamin B12 deficiency have pernicious anemia? Journal of Oral Pathology & Medicine 45:23-7.(SCI)
  2. Sun A, Chang JYF, Chiang CP (2016). Blood examination is necessary for oral mucosal disease patients. Journal of the Formosan Medical Association 115:1-2.(SCI)
  3. Cheng SJ, Chen HM and Chiang CP (2015). Cryogun cryotherapy is the first-line treatment of choice for oral leukoplakia. Journal of Dental Sciences 10: 223-224. (SCI)
  4. Chiang ML, Hsieh YJ, Tseng YL, Lin JR and Chiang CP (2014). Oral mucosal lesions and developmental anomalies in dental patients of a teaching hospital in Northern Taiwan. Journal of Dental Sciences 9: 69-77. (SCI)
  5. Shen WR, Wang YP, Chang JYF, Yu SY, Chen HM and Chiang CP (2014). Perineural invasion and expression of nerve growth factor can predict the progression and prognosis of oral tongue squamous cell carcinoma. Journal of Oral Pathology & Medicine 43: 258-264. (SCI)
  6. Sun A, Lin HP, Wang YP, Chen HM, Cheng SJ, Chiang CP (2013). Significant reduction of serum homocysteine level and oral symptoms after different vitamin supplement treatments in patients with burning mouth syndrome. Journal of Oral Pathology & Medicine doi: 10.1111/jop.12043 (SCI)
  7. Cheng SJ, Liu YC, Cheng SL, Lee JJ, Chen HM, Chang HH, Kok SH, Kuo MYP, Chiang CP (2013). Expression of G�12 predicts progression and prognosis of oral squamous cell carcinomas in Taiwan. Journal of Oral Pathology & Medicine  DOI: 10.1111/jop.12050. (SCI)
  8. Lee JJ, Cheng SJ, Wang YP, Jeng JH, Chiang CP, Kok SH (2013). Osteonecrosis of the jaws associated with the use of yearly zoledronic acid: Report of 2 cases. Head & Neck 35(1):E6-E10. (SCI)
  9. Cheng SJ, Kok SH, Lee JJ, Kuo MYP, Cheng SL, Huang YL, Chen HM, Chang HH, Chiang CP (2012). Significant association of SRC protein expression with the progression, recurrence, and prognosis of oral squamous cell carcinoma in Taiwan. Head and Neck-Journal for the Sciences and Specialties of the Head and Neck 34(9):1340-45. (SCI)
  10. Sun AD, Lin HP, Wang YP, Chiang CP (2012). Significant association of deficiency of hemoglobin, iron and vitamin B12, high homocysteine level, and gastric parietal cell antibody positivity with atrophic glossitis. Journal of Oral Pathology & Medicine 41(6):500-04. (SCI)